Ruxandra Draghia: search on Z-Library

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1

DNA vaccination and gene therapy: optimization and delivery for cancer therapy

Bodles-Brakhop, Angela M, Draghia-Akli, Ruxandra

Journal:

Expert Review of Vaccines

Year:

2008

Language:

english

File:

PDF, 451 KB

english, 2008

2

The 2010 scientific strategic plan of the Global HIV Vaccine Enterprise

Berkley, Seth, Bertram, Kenneth, Delfraissy, Jean-François, Draghia-Akli, Ruxandra, Fauci, Anthony, Hallenbeck, Cynthia, Kagame, Madame Jeannette, Kim, Peter, Mafubelu, Daisy, Makgoba, Malegapuru W

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 254 KB

english, 2010

3

Progress in rare diseases research 2010-2016: an IRDiRC perspective

Dawkins, Hugh JS, Draghia-Akli, Ruxandra, Lasko, Paul, Lau, Lilian PL, Jonker, Anneliene H, Cutillo, Christine M, Rath, Ana, Boycott, Kym M, Baynam, Gareth, Lochmüller, Hanns, Kaufmann, Petra, Cam, Ya

Journal:

Clinical and Translational Science

Year:

2017

Language:

english

File:

PDF, 1.32 MB

english, 2017

4

A database on global health research in Africa

Collins, Francis, Beaudet, Alain, Draghia-Akli, Ruxandra, Gruss, Peter, Savill, John, Syrota, André, Dautry, Alice, Ulfendahl, Mats, Walport, Mark, Onken, James, Glass, Roger I

Journal:

The Lancet Global Health

Year:

2013

Language:

english

File:

PDF, 894 KB

english, 2013

5

IMI moves forward

Strohmeier, Rudolf, Draghia-Akli, Ruxandra, Rys, Andrzej, Silvan, Pedro Ortun, Lennon, Theodius, Incerti, Carlo, Bergström, Richard, Chibout, Salahdine, Doliveux, Roch, Andersen, Peter Hongaard

Journal:

Nature Biotechnology

Year:

2011

Language:

english

File:

PDF, 128 KB

english, 2011

6

Electroporation-Enhanced Nonviral Gene Transfer for the Prevention or Treatment of Immunological, Endocrine and Neoplastic Diseases

Prud'homme, Gerald, Glinka, Yelena, Khan, Amir, Draghia-Akli, Ruxandra

Journal:

Current Gene Therapy

Year:

2006

Language:

english

File:

PDF, 253 KB

english, 2006

7

Understanding the brain through large, multidisciplinary research initiatives

Quaglio, Gianluca, Corbetta, Maurizio, Karapiperis, Theodoros, Amunts, Katrin, Koroshetz, Walter, Yamamori, Tetsuo, Draghia-Akli, Ruxandra

Journal:

The Lancet Neurology

Year:

2017

Language:

english

File:

PDF, 41 KB

english, 2017

8

Metachromatic leukodystrophy: Identification of the first deletion in exon 1 and nine novel point mutations in the arylsulfatase A gene

Ruxandra Draghia, Franck Letourneur, Cristina Drugan, Jeanne Manicom, Christophe Blanchot, Axel Kahn, Livia Poenaru, Catherine Caillaud

Journal:

Year:

1997

Language:

english

File:

PDF, 273 KB

english, 1997

9

A look inside the framework: EU funding priorities and criteria in the health theme of the co-operation programme

Ruxandra Draghia-Akli

Journal:

Year:

2010

Language:

english

File:

PDF, 58 KB

english, 2010

10

Plasmid growth hormone releasing hormone therapy in healthy and laminitis-afflicted horses—evaluation and pilot study

Patricia A. Brown, Angela Bodles-Brakhop, Ruxandra Draghia-Akli

Journal:

The Journal of Gene Medicine

Year:

2008

Language:

english

File:

PDF, 416 KB

english, 2008

11

Gene therapy by electroporation for the treatment of chronic renal failure in companion animals

Patricia A Brown, Angela M Bodles-Brakhop, Melissa A Pope, Ruxandra Draghia-Akli

Journal:

BMC Biotechnology

Year:

2009

Language:

english

File:

PDF, 1.09 MB

english, 2009

12

The selection of experts evaluating health projects for the EU Sixth Framework Program

GianLuca Quaglio, Vincenzo Guardabasso, Ole F. Olesen, Ruxandra Draghia-Akli

Journal:

Journal of Public Health (Springer)

Year:

2011

Language:

english

File:

PDF, 199 KB

english, 2011

13

10.1038/6981

Schwartz, Robert J., Li, Xuyang, Eastman, Eric M., Draghia-Akli, Ruxandra

Journal:

Nature Biotechnology

Year:

1999

Language:

english

File:

PDF, 414 KB

english, 1999

14

10.1038/70718

Draghia-Akli, Ruxandra, Schwartz, Robert J., Fiorotto, Marta L., Hill, Leigh Anne, Malone, P. Brandon, Deaver, Daniel R.

Journal:

Nature Biotechnology

Year:

1999

Language:

english

File:

PDF, 231 KB

english, 1999

15

Enhanced growth by ectopic expression of growth hormone releasing hormone using an injectable myogenic vector

Draghia-Akli, Ruxandra, Li, Xuyang, Schwartz, Robert J.

Journal:

Nature Biotechnology

Year:

1997

File:

PDF, 705 KB

1997

16

Long-term effects of plasmid-mediated growth hormone releasing hormone in dogs

Tone, Catherine M, Cardoza, Dawn M, Carpenter, Robert H, Draghia-Akli, Ruxandra

Journal:

Cancer Gene Therapy

Year:

2004

Language:

english

File:

PDF, 137 KB

english, 2004

17

Growth hormone releasing hormone plasmid supplementation, a potential treatment for cancer cachexia, does not increase tumor growth in nude mice

Khan, Amir S, Smith, Louis C, Anscombe, Ingrid W, Cummings, Kathleen K, Pope, Melissa A, Draghia-Akli, Ruxandra

Journal:

Cancer Gene Therapy

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

18

A Comparison of the Growth Responses Following Intramuscular GHRH Plasmid Administration Versus Daily Growth Hormone Injections in Young Pigs

Khan, Amir S, Draghia-Akli, Ruxandra, Shypailo, Roman J, Ellis, Kenneth I, Mersmann, Harry, Fiorotto, Marta L

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 178 KB

english, 2009

19

High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model

Jiangmei Yin, Anlan Dai, Dominick J. Laddy, Jian Yan, Tatiana Arango, Amir S. Khan, Mark G. Lewis, Hanne Andersen, Michele A. Kutzler, Ruxandra Draghia-Akli, David B. Weiner, Jean D. Boyer

Journal:

Year:

2009

Language:

english

File:

PDF, 1.19 MB

english, 2009

20

Effects of administration of two growth hormone–releasing hormone plasmids to gilts on sow and litter performance for the subsequent three gestations

Brown, Patricia A., Khan, Amir S., Draghia-Akli, Ruxandra, Pope, Melissa A., Bodles-Brakhop, Angela M., Kern, Douglas R.

Journal:

American Journal of Veterinary Research

Year:

2012

Language:

english

File:

PDF, 397 KB

english, 2012

21

Persistent antibody and T cell responses induced by HIV-1 DNA vaccine delivered by electroporation

Anthony D. Cristillo, Deborah Weiss, Lauren Hudacik, Susana Restrepo, Lindsey Galmin, John Suschak, Ruxandra Draghia-Akli, Phillip Markham, Ranajit Pal

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 282 KB

english, 2008

22

HIV-1 Env vaccine comprised of electroporated DNA and protein co-administered with Talabostat

Anthony D. Cristillo, Lindsey Galmin, Susana Restrepo, Lauren Hudacik, John Suschak, Brad Lewis, Ruxandra Draghia-Akli, Nazneen Aziz, Deborah Weiss, Phillip Markham, Ranajit Pal

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 219 KB

english, 2008

23

Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device

Henry Hebel, Heather Attra, Amir Khan, Ruxandra Draghia-Akli

Journal:

Year:

2006

Language:

english

File:

PDF, 478 KB

english, 2006

24

Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques

Lauren A. Hirao, Ling Wu, Amir S. Khan, Abhishek Satishchandran, Ruxandra Draghia-Akli, David B. Weiner

Journal:

Year:

2008

Language:

english

File:

PDF, 489 KB

english, 2008

25

Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques

Lauren A. Hirao, Ling Wu, Amir S. Khan, David A. Hokey, Jian Yan, Anlan Dai, Michael R. Betts, Ruxandra Draghia-Akli, David B. Weiner

Journal:

Year:

2008

Language:

english

File:

PDF, 596 KB

english, 2008

26

Cellular immunity induced by a novel HPV18 DNA vaccine encoding an E6/E7 fusion consensus protein in mice and rhesus macaques

Jian Yan, Kristina Harris, Amir S. Khan, Ruxandra Draghia-Akli, Duane Sewell, David B. Weiner

Journal:

Year:

2008

Language:

english

File:

PDF, 213 KB

english, 2008

27

Parameters for DNA vaccination using adaptive constant-current electroporation in mouse and pig models

Ruxandra Draghia-Akli, Amir S. Khan, Patricia A. Brown, Melissa A. Pope, Ling Wu, Lauren Hirao, David B. Weiner

Journal:

Year:

2008

Language:

english

File:

PDF, 569 KB

english, 2008

28

Strong HCV NS3- and NS4A-specific cellular immune responses induced in mice and Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine

Krystle A. Lang, Jian Yan, Ruxandra Draghia-Akli, Amir Khan, David B. Weiner

Journal:

Year:

2008

Language:

english

File:

PDF, 946 KB

english, 2008

29

Production of pharmaceutical-grade plasmids at high concentration and high supercoiled percentage

Ying Cai, Stephen Rodriguez, Ramu Rameswaran, Ruxandra Draghia-Akli, Robert J. Juba Jr., Henry Hebel

Journal:

Year:

2010

Language:

english

File:

PDF, 694 KB

english, 2010

30

Effects of maternal plasmid GHRH treatment on offspring growth

Amir S. Khan, Angela M. Bodles-Brakhop, Marta L. Fiorotto, Ruxandra Draghia-Akli

Journal:

Year:

2010

Language:

english

File:

PDF, 250 KB

english, 2010

31

Repeated DNA therapeutic vaccination of chronically SIV-infected macaques provides additional virological benefit

Antonio Valentin, Agneta von Gegerfelt, Margherita Rosati, Georgios Miteloudis, Candido Alicea, Cristina Bergamaschi, Rashmi Jalah, Vainav Patel, Amir S. Khan, Ruxandra Draghia-Akli, George N. Pavlaki

Journal:

Year:

2010

Language:

english

File:

PDF, 1.82 MB

english, 2010

32

Systemic immunization with CCL27/CTACK modulates immune responses at mucosal sites in mice and macaques

Kimberly A. Kraynyak, Michele A. Kutzler, Neil J. Cisper, Amir S. Khan, Ruxandra Draghia-Akli, Niranjan Y. Sardesal, Mark G. Lewis, Jian Yan, David B. Weiner

Journal:

Year:

2010

Language:

english

File:

PDF, 954 KB

english, 2010

33

European Union vaccine research—An overview

Jürgen Sautter, Ole F. Olesen, Jeremy Bray, Ruxandra Draghia-Akli

Journal:

Year:

2011

Language:

english

File:

PDF, 179 KB

english, 2011

34

Electroporation for the Delivery of DNA-based Vaccines and Immunotherapeutics: Current Clinical Developments

Bodles-Brakhop, Angela M, Heller, Richard, Draghia-Akli, Ruxandra

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 930 KB

english, 2009

35

Increased immunogenicity of HIV vaccination with constant-current electroporation and molecular adjuvants in mice and rhesus macaques

Lauren Hirao, Amir Khan, Ling Wu, David Hokey, Ruxandra Draghia-Akli…

Journal:

Year:

2006

Language:

english

File:

PDF, 69 KB

english, 2006

36

Highly Efficient Constant-Current Electroporation Increases In Vivo Plasmid Expression

Khan, Amir S., Pope, Melissa A., Draghia-Akli, Ruxandra

Journal:

DNA and Cell Biology

Year:

2005

Language:

english

File:

PDF, 155 KB

english, 2005

37

EC's science-friendly future

Ruxandra Draghia-Akli

Journal:

Year:

2010

Language:

english

File:

PDF, 297 KB

english, 2010

38

Effects of Plasmid Growth Hormone–Releasing Hormone Treatment during Heat Stress

Brown, Patricia A., Bodles-Brakhop, Angela M., Draghia-Akli, Ruxandra

Journal:

DNA and Cell Biology

Year:

2008

Language:

english

File:

PDF, 172 KB

english, 2008

39

Toward an International Initiative for Traumatic Brain Injury Research

Tosetti, Patrizia, Hicks, Ramona R., Theriault, Elizabeth, Phillips, Anthony, Koroshetz, Walter, Draghia-Akli, and the Workshop Part, Ruxandra

Journal:

Journal of Neurotrauma

Year:

2013

Language:

english

File:

PDF, 553 KB

english, 2013

40

Transplacental Transfer of a Growth Hormone-Releasing Hormone Peptide from Mother to Fetus in the Rat

Fiorotto, Marta L., Lopez, Rusmely, Oliver, William T., Khan, Amir S., Draghia-Akli, Ruxandra

Journal:

DNA and Cell Biology

Year:

2006

Language:

english

File:

PDF, 395 KB

english, 2006

41

Gene and Cell Therapy Funding Opportunities in Horizon 2020: An Overview for 2014–2015

Gancberg, David, Draghia-Akli, Ruxandra

Journal:

Human Gene Therapy

Year:

2014

Language:

english

File:

PDF, 96 KB

english, 2014

42

Optimization of Electroporation Parameters for the Intramuscular Delivery of Plasmids in Pigs

Khan, Amir S., Smith, Louis C., Abruzzese, Ronald V., Cummings, Kathleen K., Pope, Melissa A., Brown, Patricia A., Draghia-Akli, Ruxandra

Journal:

DNA and Cell Biology

Year:

2003

Language:

english

File:

PDF, 215 KB

english, 2003

43

585. Improved Efficacy of DNA Vaccines for HIV and Smallpox Using Constant-Current Electroporation

Hirao, Lauren, Khan, Amir S., Draghia-Akli, Ruxandra, Weiner, David B.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 80 KB

english, 2006

44

541. Species-Specific Characteristics in Muscle Resistance and Their Impact on In Vivo Electroporation

Khan, Amir S., Brown, Patricia A., Pope, Melissa A., Draghia-Akli, Ruxandra

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

45

598. Effective Humoral and Cellular Smallpox-Immune Responses Using a Combination of Plasmids Delivered by Intramuscular Injection Followed by Constant-Current Electroporation in Rabbits

S. Khan, Amir, Hirao, Lauren, Weiner, David B., Draghia-Akli, Ruxandra

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 93 KB

english, 2006

46

Plasmid-Based Expression Technology Using Growth Hormone Releasing Hormone: A Novel Method for Physiologically Stimulating Long-Term Growth Hormone Secretion

Draghia-Akli, Ruxandra, Pope, Melissa, Brown, Patricia, Khan, Amir

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2006

Language:

english

File:

PDF, 159 KB

english, 2006

47

Growth Hormone–releasing Hormone Plasmid Treatment by Electroporation Decreases Offspring Mortality Over Three Pregnancies

Person, Ryan, Bodles-Brakhop, Angela M, Pope, Melissa A, Brown, Patricia A, Khan, Amir S, Draghia-Akli, Ruxandra

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 201 KB

english, 2008

48

Better Safe Than Sorry: Ethics Review in European Union-Funded Health Research

Draghia-Akli, Ruxandra, Hoeveler, Arnd, Löffler, Peter, Namorado, Joana

Journal:

Stem Cells and Development

Year:

2014

Language:

english

File:

PDF, 246 KB

english, 2014

49

Opportunities for vaccine research in Europe

Gancberg, David, Hoeveler, Arnd, Martini, Alessandra, Draghia-Akli, Ruxandra

Journal:

Human Vaccines & Immunotherapeutics

Year:

2015

Language:

english

File:

PDF, 427 KB

english, 2015

50

Comparative Analysis of Immune Responses Induced by Vaccination With SIV Antigens by Recombinant Ad5 Vector or Plasmid DNA in Rhesus Macaques

Hirao, Lauren A, Wu, Ling, Satishchandran, Abhishek, Khan, Amir S, Draghia-Akli, Ruxandra, Finnefrock, Adam C, Bett, Andrew J, Betts, Michael R, Casimiro, Danilo R, Sardesai, Niranjan Y, Kim, J Joseph

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 398 KB

english, 2010